You can set goals to obtain any of the Achievements that are available in the game. If you are able to focus your efforts then you will be able to reach each of the achievements that are available.
I am currently very near reaching the 200+ Airbus Acheivement. But it may be a while till I change my fleet and reach the 200+ Antonov achievement.
But with time you can and will be able to knock them out one by one.